Before two strokes became the predominant technology in motorcycle Grand Prix racing, and before the Japanese aggressively attacked the high displacement classes, there was really only one name in the 500 cc motorcycle Grand Prix World Championships - MV Agusta.
The Italian motorcycle builder was truly in a class of their own. They won 18 world championships in the 500 cc class between 1956 and 1974. You'll notice that is only one year during that span– 1957 – they did not win. As if that weren't enough, in 1956, 1958, 1959, and 1960, they won the 125 cc, 250 cc, and 500 cc classes collectively. Outright dominance.